Chewing the fat for Akt1 inhibition and oncosuppression

The catabolic and energy-dissipating actions of mitochondrial uncoupling proteins (UCPs) conflict with many of the bioenergetic hallmarks of malignancy. We have recently demonstrated that overexpression of mitochondrial uncoupling protein 3 (Ucp3) in the basal epidermis impedes skin tumorigenesis th...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Nowinski, Sara M., Solmonson, Ashley, Mills, Edward M.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905408/
https://ncbi.nlm.nih.gov/pubmed/27308618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1102795
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