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ATM: An unexpected tumor-promoting factor in HER2-expressing tumors
ATM kinase is a gatekeeper of genome stability. However, its role in several other signaling pathways suggests that it might not always act as a tumor suppressor. Here, we discuss recent data that unveil a function of ATM as a tumor promoter in HER2-positive breast cancer.
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905372/ https://ncbi.nlm.nih.gov/pubmed/27308589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1054551 |
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