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Boosting NAD(+) for the prevention and treatment of liver cancer

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide yet has limited therapeutic options. We recently demonstrated that inhibition of de novo nicotinamide adenine dinucleotide (NAD(+)) synthesis is responsible for DNA damage, thereby initiating hepatocarcinogenesis. We...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Hovedforfatter: Djouder, Nabil
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905329/
https://ncbi.nlm.nih.gov/pubmed/27308492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2014.1001199
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