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Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression

Hematopoietic stressors such as infection, bleeding, or toxic injury trigger a hematopoietic adaptation that sacrifices hematopoietic stem and progenitor cell (HSPC) quiescence to meet an urgent need for new blood cell production. Once the hematopoietic demands are adequately met, homeostasis must b...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Brenet, Fabienne, Scandura, Joseph M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905289/
https://ncbi.nlm.nih.gov/pubmed/27308454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.978703
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