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Switching Rho GTPase activation into effective antibacterial defenses requires the caspase-1/IL-1beta signaling axis
The monitoring of the activation state of Rho GTPases has emerged as a potent innate immune mechanism for detecting pathogens. In the March issue of PLOS Pathogens, we show that the activation of Rho GTPases by the CNF1 toxin during E. coli-triggered bacteremia leads to a GR1(+)cell-mediated efficie...
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| Publicat a: | Small GTPases |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905264/ https://ncbi.nlm.nih.gov/pubmed/26492464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2015.1095698 |
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