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Noxa and cancer therapy: Tuning up the mitochondrial death machinery in response to chemotherapy

Biochemical analyses have characterized the BH3-only protein family member Noxa as a “sensitizer” with weak pro-apoptotic activity. Investigations into cancer cell responses to chemotherapeutic agents have identified Noxa as a pivotal factor mediating the cytotoxic effect of a plethora of anticancer...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Albert, Marie-Christine, Brinkmann, Kerstin, Kashkar, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905168/
https://ncbi.nlm.nih.gov/pubmed/27308315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mco.29906
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