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Functional characterization of ENPP1 reveals a link between cell cycle progression and stem-like phenotype in glioblastoma

A high-throughput phenotypic screen in glioblastoma stem-like cells (GSCs) identified a novel molecular mechanism in which ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) plays an important role in balancing the pool of nucleotides, thus maintaining GSCs in an undifferentiated proliferati...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Bageritz, Josephine, Goidts, Violaine
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905057/
https://ncbi.nlm.nih.gov/pubmed/27308351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.964028
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