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Harnessing the nuclear receptor PPARγ to inhibit the growth of lung adenocarcinoma by rewiring metabolic circuitries

Altered metabolism and nuclear receptor activity have been reported in various cancer types. Here, we discuss our recent finding that the metabolic state of lung adenocarcinoma cells expressing the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) can be modulated by thiazoli...

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Publicat a:Mol Cell Oncol
Autors principals: Yenerall, Paul, Kittler, Ralf
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905022/
https://ncbi.nlm.nih.gov/pubmed/27308443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.980660
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