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High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor

Genetically encoded voltage indicators (GEVIs) are a promising technology for fluorescence readout of millisecond-scale neuronal dynamics. Previous GEVIs had insufficient signaling speed and dynamic range to resolve action potentials in live animals. We coupled fast voltage-sensing domains from a rh...

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Bibliographic Details
Published in:Science
Main Authors: Gong, Yiyang, Huang, Cheng, Li, Jin Zhong, Grewe, Benjamin F., Zhang, Yanping, Eismann, Stephan, Schnitzer, Mark J.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904846/
https://ncbi.nlm.nih.gov/pubmed/26586188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0810
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