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Class A scavenger receptor-mediated dsRNA internalization is independent of innate antiviral signaling and does not require PI3K activity()

Double-stranded RNA is a potent trigger of innate immune signaling, eliciting effects within virally infected cells and following release from dying cells. Given its inherent stability, extracellular dsRNA induces both local and systemic effects. Although the class A scavenger receptors (SR-As)() me...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Nellimarla, Srinivas, Baid, Kaushal, Loo, Yueh-Ming, Gale, Michael, Bowdish, Dawn M., Mossman, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904834/
https://ncbi.nlm.nih.gov/pubmed/26363049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501028
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