High-Throughput Single-Cell Derived Sphere Formation for Cancer Stem-Like Cell Identification and Analysis

Considerable evidence suggests that many malignancies are driven by a cellular compartment that displays stem cell properties. Cancer stem-like cells (CSCs) can be identified by expression of cell surface markers or enzymatic activity, but these methods are limited by phenotypic heterogeneity and pl...

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Udgivet i:Sci Rep
Main Authors: Chen, Yu-Chih, Ingram, Patrick N., Fouladdel, Shamileh, McDermott, Sean P., Azizi, Ebrahim, Wicha, Max S., Yoon, Euisik
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904376/
https://ncbi.nlm.nih.gov/pubmed/27292795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27301
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