Neuronal Wiskott–Aldrich syndrome protein regulates TGF-β1–mediated lung vascular permeability

TGF-β1 induces an increase in paracellular permeability and actin stress fiber formation in lung microvascular endothelial and alveolar epithelial cells via small Rho GTPase. The molecular mechanism involved is not fully understood. Neuronal Wiskott–Aldrich syndrome protein (N-WASP) has an essential...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Wagener, Brant M., Hu, Meng, Zheng, Anni, Zhao, Xueke, Che, Pulin, Brandon, Angela, Anjum, Naseem, Snapper, Scott, Creighton, Judy, Guan, Jun-Lin, Han, Qimei, Cai, Guo-Qiang, Han, Xiaosi, Pittet, Jean-Francois, Ding, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904290/
https://ncbi.nlm.nih.gov/pubmed/27025963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600102R
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