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Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation

Enhancing the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) will facilitate their applications in disease modeling and drug discovery. Previous studies suggest that cell alignment could enhance hPSC-CM maturation; however, the robustness of this approach has not been we...

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Pubblicato in:Stem Cell Res
Autori principali: Han, Jingjia, Wu, Qingling, Xia, Younan, Wagner, Mary B, Xu, Chunhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903921/
https://ncbi.nlm.nih.gov/pubmed/27131761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.04.014
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