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Electrospun fibrous scaffolds promote breast cancer cell alignment and epithelial-mesenchymal transition

In this work we created electrospun fibrous scaffolds with random and aligned fiber orientations in order to mimic the 3D structure of the natural extracellular matrix (ECM). The rigidity and topography of the ECM environment have been reported to alter cancer cell behavior. But the complexity of th...

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Detalhes bibliográficos
Main Authors: Saha, Sharmistha, Duan, Xinrui, Wu, Laying, Lo, Pang-Kuo, Chen, Hexin, Wang, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269532/
https://ncbi.nlm.nih.gov/pubmed/22182057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la203846w
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