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Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation

Enhancing the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) will facilitate their applications in disease modeling and drug discovery. Previous studies suggest that cell alignment could enhance hPSC-CM maturation; however, the robustness of this approach has not been we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Res
Hauptverfasser: Han, Jingjia, Wu, Qingling, Xia, Younan, Wagner, Mary B, Xu, Chunhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903921/
https://ncbi.nlm.nih.gov/pubmed/27131761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2016.04.014
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