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Increased p38 mitogen-activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures

The pathological basis of neonatal hypoxia–ischemia (HI) brain damage is characterized by neuronal cell loss. Oxidative stress is thought to be one of the main causes of HI-induced neuronal cell death. The p38 mitogen-activated protein kinase (MAPK) is activated under conditions of cell stress. Howe...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Neurosci
Hauptverfasser: Lu, Qing, Rau, Thomas F., Harris, Valerie, Johnson, Maribeth, Poulsen, David J., Black, Stephen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903872/
https://ncbi.nlm.nih.gov/pubmed/21939459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2011.07786.x
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