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Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells

BACKGROUND: Phytanic acid (PA) has been implicated in development of cancer and its defective metabolism is known to cause life-threatening conditions, such as Refsum disease, in children. To explore molecular mechanisms of phytanic acid-induced cellular pathology, we investigated its effect on NADP...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Dhaunsi, Gursev S., Alsaeid, Mayra, Akhtar, Saghir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902935/
https://ncbi.nlm.nih.gov/pubmed/27287039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-016-0273-9
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