Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study

BACKGROUND: GLP-1 agonists, including liraglutide, have emerged as effective therapies for type 2 diabetes (DM) and obesity. Here, we attempted to delineate how liraglutide, at doses approved for DM, may impact circulating hormones influencing energy homeostasis in diabetics. BASIC PROCEDURES: Using...

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Detalhes bibliográficos
Publicado no:Metabolism
Main Authors: Farr, Olivia M., Tsoukas, Michael A., Triantafyllou, Georgios, Dincer, Fadime, Filippaios, Andreas, Ko, Byung-Joon, Mantzoros, Christos S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902873/
https://ncbi.nlm.nih.gov/pubmed/27282865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2016.03.009
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