Acute Pergolide Exposure Stiffens Engineered Valve Interstitial Cell Tissues and Reduces Contractility In Vitro

Medications based on ergoline-derived dopamine and serotonin agonists are associated with off-target toxicities that include valvular heart disease (VHD). Reports of drug-induced VHD resulted in the withdrawal of appetite suppressants containing fenfluramine and phentermine from the U.S. market in 1...

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Bibliographic Details
Published in:	Cardiovasc Pathol
Main Authors:	Capulli, Andrew K., MacQueen, Luke A., O’Connor, Blakely B., Dauth, Stephanie, Parker, Kevin Kit
Format:	Artigo
Language:	Inglês
Published:	2016
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4902741/ https://ncbi.nlm.nih.gov/pubmed/27174867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2016.04.004
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Acute Pergolide Exposure Stiffens Engineered Valve Interstitial Cell Tissues and Reduces Contractility In Vitro

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