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Detection of influenza antigenic variants directly from clinical samples using polyclonal antibody based proximity ligation assays

Identification of antigenic variants is the key to a successful influenza vaccination program. The empirical serological methods to determine influenza antigenic properties require viral propagation. Here a novel quantitative PCR-based antigenic characterization method using polyclonal antibody and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Virology
Hauptverfasser: Martin, Brigitte E., Jia, Kun, Sun, Hailiang, Ye, Jianqiang, Hall, Crystal, Ware, Daphne, Wan, Xiu-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902327/
https://ncbi.nlm.nih.gov/pubmed/25546251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.11.029
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