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SnoN antagonizes the Hippo kinase complex to promote TAZ signaling during breast carcinogenesis
SnoN regulates multiple signaling pathways including TGFβ/Smad and p53 and displays both pro-oncogenic and anti-oncogenic activities in human cancer. We have observed previously that both its intracellular localization and expression levels are sensitive to cell density, suggesting that it may cross...
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| Udgivet i: | Dev Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4902294/ https://ncbi.nlm.nih.gov/pubmed/27237790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.05.002 |
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