Impairment of Angiogenic Sphingosine Kinase-1/Sphingosine-1-Phosphate Receptors Pathway in Preeclampsia

Preeclampsia (PE), is a serious pregnancy disorder characterized in the early gestation by shallow trophoblast invasion, impaired placental neo-angiogenesis, placental hypoxia and ischemia, which leads to maternal and fetal morbidity and mortality. Here we hypothesized that angiogenic sphingosine ki...

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Udgivet i:PLoS One
Main Authors: Dobierzewska, Aneta, Palominos, Macarena, Sanchez, Marianela, Dyhr, Michael, Helgert, Katja, Venegas-Araneda, Pia, Tong, Stephen, Illanes, Sebastian E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902228/
https://ncbi.nlm.nih.gov/pubmed/27284992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157221
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