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Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice

Immunoglobulin A (IgA), the major class of antibody secreted by the gut mucosa, is an important contributor to gut barrier function(1–3). The repertoire of IgA bound to gut bacteria reflects both T cell-dependent and -independent pathways(4,5), plus glycans present on the antibody’s secretory compon...

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Publicado en:Nature
Autores principales: Planer, Joseph D., Peng, Yangqing, Kau, Andrew L., Blanton, Laura V., Ndao, I. Malick, Tarr, Phillip I., Warner, Barbara B., Gordon, Jeffrey I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902178/
https://ncbi.nlm.nih.gov/pubmed/27279225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17940
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