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Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells

Tumor side population (SP) cells display stem-like properties that can be modulated by treatment with the calcium channel blocker verapamil. Verapamil can enhance the cytotoxic effects of chemotherapeutic drugs and multi-drug resistance by targeting the transport function of the P-glycoprotein (P-gp...

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Publicat a:Int J Oncol
Autors principals: ZHAO, LU, ZHAO, YUE, SCHWARZ, BETTINA, MYSLIWIETZ, JOSEF, HARTIG, ROLAND, CAMAJ, PETER, BAO, QI, JAUCH, KARL-WALTER, GUBA, MAKUS, ELLWART, JOACHIM WALTER, NELSON, PETER JON, BRUNS, CHRISTIANE JOSEPHINE
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902079/
https://ncbi.nlm.nih.gov/pubmed/27177126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3512
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