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Osteopontin is elevated in patients with mitral annulus calcification independent from classic cardiovascular risk factors

BACKGROUND: Osteopontin (OPN) regulates the Ca(++)-deposition in bone and coronary arteries. Elevated OPN were also associated with (aortic) valve calcification in healthy individuals. This study aimed to investigate the association between OPN levels and mitral annulus calcification (MAC) in patien...

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Pubblicato in:BMC Cardiovasc Disord
Autori principali: Sponder, Michael, Reuter, Christian, Fritzer-Szekeres, Monika, Litschauer, Brigitte, Binder, Thomas, Strametz-Juranek, Jeanette
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901469/
https://ncbi.nlm.nih.gov/pubmed/27283399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-016-0314-3
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