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Study design and data analysis considerations for the discovery of prognostic molecular biomarkers: a case study of progression free survival in advanced serous ovarian cancer

BACKGROUND: Accurate discovery of molecular biomarkers that are prognostic of a clinical outcome is an important yet challenging task, partly due to the combination of the typically weak genomic signal for a clinical outcome and the frequently strong noise due to microarray handling effects. Effecti...

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Publicat a:BMC Med Genomics
Autors principals: Qin, Li-Xuan, Levine, Douglas A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901402/
https://ncbi.nlm.nih.gov/pubmed/27282150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0187-4
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