Identification of circulating microRNAs during the liver neoplastic process in a murine model of hereditary tyrosinemia type 1

Hereditary tyrosinemia type 1 (HT1) is a severe inborn error of metabolism, impacting the tyrosine catabolic pathway with a high incidence of hepatocellular carcinoma (HCC). Using a HT1 murine model, we investigated the changes in profiles of circulating and hepatic miRNAs. The aim was to determine...

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Pubblicato in:Sci Rep
Autori principali: Angileri, Francesca, Morrow, Geneviève, Scoazec, Jean-Yves, Gadot, Nicolas, Roy, Vincent, Huang, Suli, Wu, Tangchun, Tanguay, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901289/
https://ncbi.nlm.nih.gov/pubmed/27282650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27464
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