The inflammatory preatherosclerotic remodeling induced by intermittent hypoxia is attenuated by RANTES/CCL5 inhibition

RATIONALE: The highly prevalent obstructive sleep apnea syndrome (OSA) with its main component intermittent hypoxia (IH) is a risk factor for cardiovascular mortality. The poor knowledge of its pathophysiology has limited the development of specific treatments, whereas the gold standard treatment, c...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Arnaud, Claire, Beguin, Pauline, Lantuejoul, Sylvie, Pepin, Jean-Louis, Guillermet, Christiane, Pelli, Graziano, Burger, Fabienne, Buatois, Vanessa, Ribuot, Christophe, Baguet, Jean-Philippe, Mach, François, Levy, Patrick, Dematteis, Maurice
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901161/
https://ncbi.nlm.nih.gov/pubmed/21680945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201012-2033OC
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