TET2 Negatively Regulates Nestin Expression in Human Melanoma

Although melanoma is an aggressive cancer, the understanding of the virulence-conferring pathways involved remains incomplete. We have demonstrated that loss of ten-eleven translocation methylcytosine dioxygenase (TET2)-mediated 5-hydroxymethylcytosine (5-hmC) is an epigenetic driver of melanoma gro...

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Detalles Bibliográficos
Publicado en:Am J Pathol
Autores principales: Gomes, Camilla B.F., Zechin, Karina G., Xu, Shuyun, Stelini, Rafael F., Nishimoto, Ines N., Zhan, Qian, Xu, Ting, Qin, Gungwei, Treister, Nathaniel S., Murphy, George F., Lian, Christine G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2016
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901139/
https://ncbi.nlm.nih.gov/pubmed/27102770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.01.020
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