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Fas Regulates Macrophage Polarization and Fibrogenic Phenotype in a Model of Chronic Ethanol-Induced Hepatocellular Injury

The role of Fas-mediated apoptosis and its effect on proinflammatory cytokine production in early alcoholic liver disease has not been addressed. Wild-type mice (C57Bl/6) or mice with a functional mutation in the Fas ligand (B6.gld) were given either high-fat control diet or ethanol diet by intragas...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Isayama, Fuyumi, Moore, Sherri, Hines, Ian N., Wheeler, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901134/
https://ncbi.nlm.nih.gov/pubmed/27102767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.02.006
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