Zika virus targets human STAT2 to inhibit type I interferon signaling

The ongoing epidemic of Zika virus (ZIKV) illustrates the importance of flaviviruses as emerging human pathogens. All vector-borne flaviviruses studied thus far have to overcome type I interferon (IFN) to replicate and cause disease in vertebrates. The mechanism(s) by which ZIKV antagonizes IFN sign...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Grant, Alesha, Ponia, Sanket S., Tripathi, Shashank, Balasubramaniam, Vinod, Miorin, Lisa, Sourisseau, Marion, Schwarz, Megan C., Sánchez-Seco, Mari Paz, Evans, Matthew J., Best, Sonja M., García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900918/
https://ncbi.nlm.nih.gov/pubmed/27212660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.05.009
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