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Activation of human T cells in hypertension: Studies of Humanized Mice and Hypertensive Humans

Emerging evidence supports an important role for T cells in the genesis of hypertension. Because this work has predominantly been performed in experimental animals, we sought to determine whether human T cells are activated in hypertension. We employed a humanized mouse model in which the murine imm...

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Publicado en:Hypertension
Main Authors: Itani, Hana A., McMaster, William G., Saleh, Mohamed A., Nazarewicz, Rafal R., Mikolajczyk, Tomasz P., Kaszuba, Anna, Konior, Anna, Prejbisz, Aleksander, Januszewicz, Andrzej, Norlander, Allison E., Chen, Wei, Bonami, Rachel H., Marshall, Andrew F., Poffenberger, Greg, Weyand, Cornelia M., Madhur, Meena S., Moore, Daniel J., Harrison, David G., Guzik, Tomasz J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900908/
https://ncbi.nlm.nih.gov/pubmed/27217403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07237
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