Brain Region-specific Organoids using Mini-bioreactors for Modeling ZIKV Exposure

Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new platform to investigate human brain development. High cost, variability and tissue heterogeneity limit their broad applications. Here we developed a miniaturized spinning bioreactor (SpinΩ) to generate forebrain-s...

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Pubblicato in:Cell
Autori principali: Qian, Xuyu, Nguyen, Ha Nam, Song, Mingxi M., Hadiono, Christopher, Ogden, Sarah C., Hammack, Christy, Yao, Bing, Hamersky, Gregory, Jacob, Fadi, Zhong, Chun, Yoon, Ki-jun, Jeang, William, Lin, Li, Li, Yujing, Thakor, Jai, Berg, Daniel, Zhang, Ce, Kang, Eunchai, Chickering, Michael, Naeun, David, Ho, Cheng-Ying, Wen, Zhexing, Christian, Kimberly M., Shi, Pei-Yong, Maher, Brady J., Wu, Hao, Jin, Peng, Tang, Hengli, Song, Hongjun, Ming, Guo-li
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900885/
https://ncbi.nlm.nih.gov/pubmed/27118425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.032
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