NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice

AIMS: Endothelial dysfunction is an early step in the development of atherosclerosis. Increased formation of superoxide anions by NADPH oxidase Nox1, 2, and 5 reduces nitric oxide availability and can promote endothelial dysfunction. In contrast, recent evidence supports a vasoprotective role of H(2...

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Détails bibliographiques
Publié dans:Eur Heart J
Auteurs principaux: Langbein, Heike, Brunssen, Coy, Hofmann, Anja, Cimalla, Peter, Brux, Melanie, Bornstein, Stefan R., Deussen, Andreas, Koch, Edmund, Morawietz, Henning
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Basic Science
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900759/
https://ncbi.nlm.nih.gov/pubmed/26578199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv564
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