IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation

Interferon-inducible protein 16 (IFI16) is a member of the HIN-200 protein family, containing two HIN domains and one PYRIN domain. IFI16 acts as a sensor of viral and bacterial DNA and is important for innate immune responses. IFI16 binds DNA and binding has been described to be DNA length-dependen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hároníková, Lucia, Coufal, Jan, Kejnovská, Iva, Jagelská, Eva B., Fojta, Miroslav, Dvořáková, Petra, Muller, Petr, Vojtesek, Borivoj, Brázda, Václav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900677/
https://ncbi.nlm.nih.gov/pubmed/27280708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157156
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