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IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation
Interferon-inducible protein 16 (IFI16) is a member of the HIN-200 protein family, containing two HIN domains and one PYRIN domain. IFI16 acts as a sensor of viral and bacterial DNA and is important for innate immune responses. IFI16 binds DNA and binding has been described to be DNA length-dependen...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4900677/ https://ncbi.nlm.nih.gov/pubmed/27280708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157156 |
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