Genetic Polymorphisms of Glutathione S-Transferase P1 (GSTP1) and the Incidence of Anti-Tuberculosis Drug-Induced Hepatotoxicity

BACKGROUND: Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is one of the most common adverse effects associated with tuberculosis (TB) therapy. Animal studies have demonstrated important roles of glutathione S-transferases in the prevention of chemical-induced hepatotoxicity. The aim of this s...

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Publicat a:PLoS One
Autors principals: Wu, Shouquan, Wang, You-Juan, Tang, Xiaoyan, Wang, Yu, Wu, Jingcan, Ji, Guiyi, Zhang, Miaomiao, Chen, Guo, Liu, Qianqian, Sandford, Andrew J., He, Jian-Qing
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900521/
https://ncbi.nlm.nih.gov/pubmed/27281183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157478
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