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Synaptic circuit remodelling by matrix metalloproteinases in health and disease

Matrix metalloproteinases (MMPs) are extracellularly acting enzymes that have long been known to have deleterious roles in brain injury and disease. In particular, widespread and protracted MMP activity can contribute to neuronal loss and synaptic dysfunction. However, recent studies show that rapid...

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Detalhes bibliográficos
Publicado no:Nat Rev Neurosci
Autor principal: Huntley, George W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900464/
https://ncbi.nlm.nih.gov/pubmed/23047773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3320
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