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Lactation Is a Risk Factor of Postpartum Heart Failure in Mice with Cardiomyocyte-specific Apelin Receptor (APJ) Overexpression

The G protein-coupled receptor APJ and its ligand apelin are highly expressed in cardiovascular tissues and are associated with the regulation of blood pressure and cardiac function. Although accumulating evidence suggests that APJ plays a crucial role in the heart, it remains unclear whether up-reg...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Murata, Kazuya, Ishida, Junji, Ishimaru, Tomohiro, Mizukami, Hayase, Hamada, Juri, Saito, Chiaki, Fukamizu, Akiyoshi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900271/
https://ncbi.nlm.nih.gov/pubmed/27033703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699009
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