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Essential role of brain-derived neurotrophic factor in adult hippocampal function

Brain-derived neurotrophic factor (BDNF) regulates neuronal development and function. However, it has been difficult to discern its role in the adult brain in influencing complex behavior. Here, we use a recently developed inducible knockout system to show that deleting BDNF in broad forebrain regio...

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Autori principali: Monteggia, Lisa M., Barrot, Michel, Powell, Craig M., Berton, Olivier, Galanis, Victor, Gemelli, Terry, Meuth, Sven, Nagy, Andreas, Greene, Robert W., Nestler, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC490019/
https://ncbi.nlm.nih.gov/pubmed/15249684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402141101
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