Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites

Ethanol causes pancreatic damage by an unknown mechanism. Previously, we demonstrated that a sustained rise of the cytosolic Ca(2+) concentration ([Ca(2+)](i)) causes pancreatic acinar cell injury. Here we have investigated the effects of ethanol and its metabolites on Ca(2+) signaling in pancreatic...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Criddle, David N., Raraty, Michael G. T., Neoptolemos, John P., Tepikin, Alexei V., Petersen, Ole H., Sutton, Robert
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC490004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15247419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403431101
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