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Genetic Dissection of the Signaling Cascade that Controls Activation of the Shigella Type III Secretion System from the Needle Tip

Many Gram-negative bacterial pathogens use type III secretion systems (T3SSs) for virulence. The Shigella T3SS consists of a hollow needle, made of MxiH and protruding from the bacterial surface, anchored in both bacterial membranes by multimeric protein rings. Atop the needle lies the tip complex (...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Murillo, I., Martinez-Argudo, I., Blocker, A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899799/
https://ncbi.nlm.nih.gov/pubmed/27277624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27649
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