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Oxidized Low-Density Lipoprotein Induces Apoptosis in Cultured Neonatal Rat Cardiomyocytes by Modulating the TLR4/NF-κB Pathway

This study was designed to investigate the apoptosis induced by oxidized low-density lipoprotein (ox-LDL) in cultured neonatal rat cardiomyocytes and explore the possible mechanisms. We evaluated whether ox-LDL-induced apoptosis depended in part on the activation of toll-like receptor-4(TLR4)/Nuclea...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wang, Xiantao, Sun, Yuhan, Yang, Huafeng, Lu, Yuanxi, Li, Lang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899754/
https://ncbi.nlm.nih.gov/pubmed/27279424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27866
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