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Intrinsic Hippocampal Excitability Changes of Opposite Signs and Different Origins in CA1 and CA3 Pyramidal Neurons Underlie Aging-Related Cognitive Deficits

Aging-related cognitive deficits have been attributed to dysfunction of neurons due to failures at synaptic or intrinsic loci, or both. Given the importance of the hippocampus for successful encoding of memory and that the main output of the hippocampus is via the CA1 pyramidal neurons, much of the...

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Dades bibliogràfiques
Publicat a:Front Syst Neurosci
Autors principals: Oh, M. Matthew, Simkin, Dina, Disterhoft, John F.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899460/
https://ncbi.nlm.nih.gov/pubmed/27375440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2016.00052
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