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T-type Voltage-Sensitive Calcium Channels Mediate Mechanically-Induced Intracellular Calcium Oscillations in Osteocytes by Regulating Endoplasmic Reticulum Calcium Dynamics

One of the earliest responses of bone cells to mechanical stimuli is a rise in intracellular calcium (Ca(2+)), and osteocytes in particular exhibit robust oscillations in Ca(2+) when subjected to loading. Previous studies implicate roles for both the endoplasmic reticulum (ER) and T-Type voltage-sen...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Brown, Genevieve N., Leong, Pui L., Guo, X. Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899304/
https://ncbi.nlm.nih.gov/pubmed/27108342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.04.018
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