The Tryptophan Metabolism Enzyme, L-Kynureninase, is a Novel Inflammatory Factor in Psoriasis and other Inflammatory Diseases

BACKGROUND: Many human diseases arise from or have pathogenic contributions from a dysregulated immune response. One pathway with immunomodulatory ability is the tryptophan metabolism pathway, which promotes immune suppression via the enzyme indoleamine 2,3 dioxygenase (IDO) and subsequent productio...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Harden, Jamie L, Lewis, Steven M, Lish, Samantha R, Suárez-Fariñas, Mayte, Gareau, Daniel, Lentini, Tim, Johnson-Huang, Leanne M, Krueger, James G, Lowes, Michelle A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899291/
https://ncbi.nlm.nih.gov/pubmed/26725996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.09.055
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