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Glucose intolerance develops prior to increased adiposity and accelerated cessation of estrous cyclicity in female growth-restricted rats

BACKGROUND: The incidence of metabolic disease increases in early menopause. Low birth weight influences the age at menopause. Thus, this study tested the hypothesis that intrauterine growth restriction programs early reproductive aging and impaired glucose homeostasis in female rats. METHODS: Estro...

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Publicat a:Pediatr Res
Autors principals: Intapad, Suttira, Dasinger, John Henry, Brown, Andrew D., Fahling, Joel M., Esters, Joyee, Alexander, Barbara T.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899212/
https://ncbi.nlm.nih.gov/pubmed/26854801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.14
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