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Molecule Specific Effects of PKA-Mediated Phosphorylation on Rat Isolated Heart and Cardiac Myofibrillar Function

Increased cardiac myocyte contractility by the β-adrenergic system is an important mechanism to elevate cardiac output to meet hemodynamic demands and this process is depressed in failing hearts. While increased contractility involves augmented myoplasmic calcium transients, the myofilaments also ad...

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Détails bibliographiques
Publié dans:Arch Biochem Biophys
Auteurs principaux: Hanft, Laurin M., Cornell, T.D., McDonald, C.A., Rovetto, M.J., Emter, C.A., McDonald, Kerry S.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899148/
https://ncbi.nlm.nih.gov/pubmed/26854722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.01.019
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