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Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogramming

Even though all paradigms of stem cell therapy and regenerative medicine emerged from the study of hematopoietic stem cells (HSCs), our inability to generate these cells de novo or expand them in vitro persists. Initial efforts to obtain these cells began with the use of embryonic stem cell (ESC) an...

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Detalles Bibliográficos
Publicado en:Ann N Y Acad Sci
Autores principales: Daniel, Michael G., Lemischka, Ihor R., Moore, Kateri
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899120/
https://ncbi.nlm.nih.gov/pubmed/26748878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12989
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