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Interictal epileptiform discharges induce hippocampal-cortical coupling in temporal lobe epilepsy

Interactions between the hippocampus and cortex are critical for memory. Interictal epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but how they interact with physiological patterns of network activity is mostly undefined. We show in a rat model of temporal lob...

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Bibliographic Details
Published in:Nat Med
Main Authors: Gelinas, Jennifer N., Khodagholy, Dion, Thesen, Thomas, Devinsky, Orrin, Buzsáki, György
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899094/
https://ncbi.nlm.nih.gov/pubmed/27111281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4084
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