Phenol-Soluble Modulins Contribute to Early Sepsis Dissemination Not Late Local USA300-Osteomyelitis Severity in Rabbits

INTRODUCTION: In bone and joint infections (BJIs), bacterial toxins are major virulence factors: Panton—Valentine leukocidin (PVL) expression leads to severe local damage, including bone distortion and abscesses, while α-hemolysin (Hla) production is associated with severe sepsis-related mortality....

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Gepubliceerd in:PLoS One
Hoofdauteurs: Davido, Benjamin, Saleh-Mghir, Azzam, Laurent, Frédéric, Danel, Claire, Couzon, Florence, Gatin, Laure, Vandenesch, François, Rasigade, Jean-Philippe, Crémieux, Anne-Claude
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898696/
https://ncbi.nlm.nih.gov/pubmed/27275944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157133
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